Study to assess drug concentrations in plasma of different extended-release formulations of AZD1305

Exclusion Criteria

• - History or presence of any clinically significant disease or disorder in
• the opinion of the investigator.
• - Use of nicotine in the last 4 weeks before screening and not more than 7
• cigarettes per week (equivalent to 1 nicotine patch or 7 nicotine gums per
• week) before then. There will be no smoking until follow-up visit.
• - Any clinically relevant abnormal findings in physical examination, clinical
• chemistry, haematology, urinalysis, vital signs or ECG at baseline in the
• opinion of the investigator.